Neuregulin 1 anticorps (AA 21-242)

N° du produit ABIN6654437

Cet anticorps anti-Neuregulin 1 est un anticorps Souris Monoclonal détectant Neuregulin 1 dans IHC (p). Adapté pour Humain.

Aperçu rapide pour Neuregulin 1 anticorps (AA 21-242) (ABIN6654437)

Antigène: Neuregulin 1 (NRG1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Neuregulin 1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: NRG1-2752

Détail du produit anti-Neuregulin 1 anticorps

Épitope: AA 21-242

Purification: Purified

Pureté: Protein G affinity chromatography

Immunogène: A portion of amino acids 21-242 from the human protein was used as the immunogen for this Neuregulin-1 antibody.

Isotype: IgG

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Neuregulin-1 antibody to be titered up or down for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunofluorescence: 1-2 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Neuregulin-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur Neuregulin 1

Antigène: Neuregulin 1 (NRG1)

Autre désignation: Neuregulin-1 / NRG1

Sujet: Heregulin-1 / Neuregulin-1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation